Cu (II) Complex of 1- Naphthaldehyde Semicarbazone: Synthesis, Characterization, Thermal Analysis and Antibacterial Activity
Dipta Sarker
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Faruk Hossen
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Kudrat-E-Zahan
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Masuqul Haque
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Rausan Zamir
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Ali Asraf *
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
The ligand, L is the Schiff base formed by condensation of 1- naphthaldehyde with semicarbazide and its Cu(II) complex have been synthesized and characterized by elemental and thermogravimetric analysis and molar conductivity, magnetic and spectroscopic measurements. Elemental analysis of the chelate suggests the stoichiometry is 1:1 (metal-ligand). Infrared spectra of the complex agree with the coordination to the central metal atom through the nitrogen of the azomethine (-HC=N-) group and the carbonyl oxygen atom. Magnetic susceptibility data suggest a tetrahedral geometry for the complex. ESI-MS data also supports the proposed structure of the synthesized compounds. The ligand and its copper complex have been screened for their antibacterial activity against Enterobacter aerogenes and Bacillus cereus. The metal complex were shown to possess more antibacterial activity than the uncomplexed ligand.
Keywords: Semicarbazone, complexation, thermogravimetric analysis, antibacterial activity